𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Adenovirus-mediated wild-type P53 expression suppresses growth of lung adeno-carcinoma cells

✍ Scribed by Jian Li; Yongjing Xia; Lei Jiang; Hongxia Li; Yajun Hu; Lin Yi; Shixue Hu; Hongji Xu


Publisher
Chinese Anti-Cancer Association
Year
1998
Tongue
English
Weight
436 KB
Volume
10
Category
Article
ISSN
1000-9604

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Tissue-specific growth suppression and c
✍ G W Xu; Z T Sun; K Forrester; X W Wang; J Coursen; C C Harris πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 646 KB

HCC patients are generally resistant to chemotherapy, Selective expression of cytotoxic gene products in tuwhich, in some cases, may be the result of a loss of function mor cells is one of the goals of gene therapy for treating mutation in the p53 gene. cancer. We are developing such a strategy for

Frequent expression of Bcl-2 in renal-ce
✍ Yoshihiko Tomita; Vladimir Bilim; Takashi Kawasaki; Kota Takahashi; Ismail Okan; πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 French βš– 498 KB πŸ‘ 1 views

The p53 tumor-suppressor gene is the most commonly mutated gene in cancer. However, p53 gene alterations are infrequent in renal-cell cancer (RCC). Bcl-2 has been shown to inhibit apoptosis triggered by wild-type p53 and an inverse correlation between Bcl-2 expmrion and p53 mutation has been observe

Introduction of wild-type p53 gene downr
✍ Li, M. ;Gu, F. L. ;Li, W. B. ;Song, Y. S. ;Zhou, A. R. ;Guo, Y. L. πŸ“‚ Article πŸ“… 1995 πŸ› Springer 🌐 English βš– 460 KB

Retroviral vectors were used to introduce the wild-type p53 gene into human bladder cancer cell lines BIU-87 and EJ, which express endogenous wt-p53 gene and have a mutation in H-ras gene. The expression of the exogenous wt-p53 gene in cells suppresses the growth of the bladder cancer cells in stand