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Adenovirus-Mediated Hepatocyte Growth Factor Gene Transfer Prevents Lethal Liver Failure in Rats

โœ Scribed by Takahiro Nomi; Goshi Shiota; Masato Isono; Kenzo Sato; Hironaka Kawasaki

Book ID
115586873
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
167 KB
Volume
278
Category
Article
ISSN
0006-291X

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Sepsis and endotoxemia are involved in the development of fulminant hepatic failure, the prognosis of which is extremely poor and the mortality is high, with no available effective therapy. Here, we report that hepatocyte growth factor (HGF) exerts potent antiapoptotic effects in vivo and effectivel