Differentiation therapy of hepatocellula
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Chuan Yin; Yong Lin; Xin Zhang; Yue-Xiang Chen; Xin Zeng; Hai-Yan Yue; Jun-Liang
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Article
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2008
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John Wiley and Sons
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English
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Previous studies have shown that hepatocyte nuclear factor-4โฃ (HNF4โฃ) is a central regulator of differentiated hepatocyte phenotype and forced expression of HNF4โฃ could promote reversion of tumors toward a less invasive phenotype. However, the effect of HNF4โฃ on cancer stem cells (CSCs) and the trea