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Adenovirus-mediated gene transfer to human lens epithelial cells in organ culture

โœ Scribed by Louis M Carrington; Tom Southgate; Lisa A Saxby; Khaled Abul-Hassan; Tricia C Maleniak; Maria G Castro; Michael E Boulton


Book ID
117584450
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
532 KB
Volume
26
Category
Article
ISSN
0886-3350

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The human retinal pigment epithelium (RPE) is a potential target tissue for directed transfer of candidate genes to treat age-related macular degeneration (AMD). The RPE is uniquely suited to gene therapy protocols that use liposome-mediated DNA transfer because of its high intrinsic phagocytic func