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Polycations increase the efficiency of adenovirus-mediated gene transfer to epithelial and endothelial cells in vitro

✍ Scribed by Arcasoy, S M; Latoche, J D; Gondor, M; Pitt, B R; Pilewski, J M


Book ID
110037963
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
523 KB
Volume
4
Category
Article
ISSN
0969-7128

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## Abstract We report here a method that allows fast, efficient, and low‐cost screening for gene function in the vascular system of the vertebrate embryo. Through intracardiac delivery of nucleic acids optimally compacted by a specific cationic lipid, we are able to induce in vivo endothelial cell‐