✦ LIBER ✦

Adenovirus-E1A proteins transform cells by sequestering regulatory proteins

✍ Scribed by D. S. Peeper; A. Zantema

Publisher: Springer
Year: 1993
Tongue: English
Weight: 1021 KB
Volume: 17
Category: Article
ISSN: 0301-4851
DOI: 10.1007/bf00986728

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Low-level β1 protein kinase C expression

Low-level β1 protein kinase C expression in cloned rat embryo fibroblast cells enhances transformation induced by the adenovirus type 5 E1A gene

✍ Zao-Zhong Su; Gregory J. Duigou; Paul B. Fisher 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 935 KB

Expression of the E1A gene of adenovirus type 5 (Ad5) in a cloned rat embryo fibroblast (CREF) cell line results in morphological transformation. The efficiency of E1A-mediated transformation of CREF cells is increased if a wild-type Ad5 E1A gene is cotransfected with a rat beta 1 protein kinase C (

Adenovirus E1A proteins direct subcellul

Adenovirus E1A proteins direct subcellular redistribution of Nek9, A NimA-related kinase

✍ Peter Pelka; Anthony Scimè; Christina Mandalfino; Monica Joch; Parween Abdulla; 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 629 KB

## Abstract A monoclonal antibody raised against adenovirus E1A‐associated cellular proteins recognized Nek9, a NimA‐related protein kinase. Subcellular fractionation and immunofluorescence indicated that Nek9 was primarily cytoplasmic with a small portion located in the nucleus whereas E1A was pri

Negative regulation of hepatocellular ca

Negative regulation of hepatocellular carcinoma cell growth by signal regulatory protein α1

✍ He-Xin Yan; Hong-Yang Wang; Rui Zhang; Lei Chen; Bao-An Li; Shu-Qin Liu; Hui-Fan 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 571 KB

Signal regulatory protein (SIRP) ␣1 is a member of the SIRP family that undergoes tyrosine phosphorylation and binds SHP-2 tyrosine phosphatase in response to various mitogens. The expression levels of SIRP␣1 were decreased in HCC tissues, compared with the matched normal tissues. Exogenous expressi

Cell cycle regulatory protein p27KIP1 is

Cell cycle regulatory protein p27KIP1 is a substrate and interacts with the protein kinase CK2

✍ Julio C. Tapia; Victor M. Bolanos-Garcia; Muhammed Sayed; Catherine C. Allende; 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 508 KB

## Abstract The protein kinase CK2 is constituted by two catalytic (α and/or α′) and two regulatory (β) subunits. CK2 phosphorylates more than 300 proteins with important functions in the cell cycle. This study has looked at the relation between CK2 and p27^KIP1^, which is a regulator of the cell c

Suppression of tissue factor expression,

Suppression of tissue factor expression, cofactor activity, and metastatic potential of murine melanoma cells by the N-terminal domain of adenovirus E1A 12S protein

✍ Constanze Voigtländer; Arlymae Rand; Su-Ling Liu; Timothy J. Wilson; Mark R. Pit 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 386 KB

## Abstract Tissue factor, the cellular initiator of blood coagulation, has been implicated as a determinant of metastatic potential in human melanoma cells. Here, we report that differential expression of tissue factor in murine melanoma cell lines of known metastatic behavior is mediated by AP‐1‐

Expression of cell-cycle regulatory prot

Expression of cell-cycle regulatory proteins cyclin D1, cyclin E, and their inhibitor p21 WAF1/CIP1 in gastric cancer

✍ M�ller, Wolfram; Noguchi, Tsuyoshi; Wirtz, Hans-Christian; Hommel, Gerhard; Gabb 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 344 KB 👁 3 views

The expression and prognostic role of cyclin D1, cyclin E, and p21 (WAF1/CIP1) were immunohistochemically investivated in 413 curatively resected gastric carcinomas. p21 was expressed in 65•4 per cent (n=270), cyclin D1 in 23•7 per cent (n=98), and cyclin E in 13•6 per cent (n=56) of the tumours. Th