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Adenoviral delivery of B7–1 (CD80) increases the immunogenicity of human ovarian and cervical carcinoma cells

✍ Scribed by Gilligan, M G; Knox, P; Weedon, S; Barton, R; Kerr, D J; Searle, P; Young, L S


Book ID
110038227
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
318 KB
Volume
5
Category
Article
ISSN
0969-7128

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Costimulation mediated by costimulatory molecules, such as B7-1 and B7-2, which are ligands for the CD28/cytolytic T lymphocyte associated antigen (CTLA)-4 counter-receptor, plays an important role in the induction of T cell-mediated antitumor immunity. We investigated the expressions of B7-1, B7-2,