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Antigenicity of human melanoma cells transfected to express the B7-1 co-stimulatory molecule (CD80) varies with the level of B7-1 expression

✍ Scribed by Donna O. McCarthy; Nicole Glowacki; Kathleen Schell; Carol A. Emler; Mark R. Albertini

Book ID
105968426
Publisher
Springer-Verlag
Year
2000
Tongue
English
Weight
359 KB
Volume
49
Category
Article
ISSN
0340-7004

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The induction of T-cell responses against tumor cells is believed to depend on both recognition of antigen and receipt of co-stimulator). signals from interaction of ligands such as B7 with its receptors CD28 or CTLA-4 on T cells. In the present study the expression of 87 on cultured human melanoma