We investigated the possible involvement of parathyroid hormone-related protein (PTHrP) in 2 cases of metastatic pancreatic neuro-endocrine tumors associated with severe hypercalcemia. Both patients displayed biochemical alterations in renal tubular reabsorption of calcium and phosphate, as well as
Adenosquamous pancreatic cancer producing parathyroid hormone-related protein
โ Scribed by Takuya Inoue; Shigeaki Nagao; Hitomi Tajima; Keisuke Okudaira; Kazutoshi Hashiguchi; Junichi Miyazaki; Koji Matsuzaki; Yoshikazu Tsuzuki; Atsushi Kawaguchi; Kazuro Itoh; Ben Hatano; Sho Ogata; Soichiro Miura
- Publisher
- Springer Japan
- Year
- 2004
- Tongue
- English
- Weight
- 377 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0944-1174
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elevate plasma calcium by promoting bone resorption and decreasing calcium ria, Australia. excretion. Assays for plasma PTH-rP fail to detect protein convincingly in normal plasma, but measurable levels have been found in up to 100% of patients with HHM, in 75% of patients with breast carcinoma met
Background. Parathyroid hormone-related protein (PTHrP) has been regarded as one of the substances causing humoral hypercalcemia of malignancy. Methods. The immunohistochemical localization of PTHrP was investigated in 33 cases of gastric cancer (4 with heterotopic ossification and 29 without heter
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