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Adenosine Deaminase Inhibitors: Synthesis and Biological Evaluation of Unsaturated, Aromatic, and Oxo Derivatives of (+)- e rythro -9-(2‘ S -Hydroxy-3‘ R -nonyl)adenine [(+)-EHNA]

✍ Scribed by Pragnacharyulu, Palle V. P.; Varkhedkar, Vaibhav; Curtis, Mark A.; Chang, I. F.; Abushanab, Elie


Book ID
126254210
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
87 KB
Volume
43
Category
Article
ISSN
0022-2623

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ChemInform Abstract: Adenosine Deaminase
✍ R. VOLPINI; E. CAMAIONI; G. LUPIDI; S. VITTORI; G. CRISTALLI 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 34 KB 👁 2 views

## Synthesis, Diastereoisomeric Resolution and Biological Activity of 1-(2-Hydroxy-3-nonyl)-1,2,4triazole-3-carboxamide. -The synthesis and diastereomeric resolution of the title carboxamides, which are good inhibitors of adenosine deaminase, is described. The erythro isomer (VIII) proves to be m