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Adenosine A2A, but not A1, receptors mediate the arousal effect of caffeine

✍ Scribed by Huang, Zhi-Li; Qu, Wei-Min; Eguchi, Naomi; Chen, Jiang-Fan; Schwarzschild, Michael A; Fredholm, Bertil B; Urade, Yoshihiro; Hayaishi, Osamu


Book ID
109940642
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
177 KB
Volume
8
Category
Article
ISSN
1097-6256

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Adenosine A2A receptor but not HIF-1 med
✍ Elena Gammella; Gaetano Cairo; Lorenza Tacchini πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 791 KB

## Abstract Tyrosine hydroxylase (TH) is the rate‐limiting enzyme in the biosynthesis of catecholamines released by oxygen‐sensitive cells in response to hypoxic conditions. Adenosine is released in response to hypoxia in the central nervous system and CGS21680, an adenosine A~2~A receptor agonist,