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Adenosine A1, but not A2, Receptor Blockade Increases Anxiety and Arousal in Zebrafish

✍ Scribed by Caio Maximino; Monica G. Lima; Karen R. M. Olivera; Domingos L. W. Picanço-Diniz; Anderson M. Herculano


Book ID
111316951
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
197 KB
Volume
109
Category
Article
ISSN
1742-7835

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## Abstract Tyrosine hydroxylase (TH) is the rate‐limiting enzyme in the biosynthesis of catecholamines released by oxygen‐sensitive cells in response to hypoxic conditions. Adenosine is released in response to hypoxia in the central nervous system and CGS21680, an adenosine A~2~A receptor agonist,