Adenocarcinoma of the stomach: Review of 1,497 cases

✍ Scribed by J. Benton Dupont Jr.; J. Rillens Lee; George R. Burton; Isidore Cohn Jr.

• Publisher: John Wiley and Sons
• Year: 1978
• Tongue: English
• Weight: 597 KB
• Volume: 41
• Category: Article
• ISSN: 0008-543X
• DOI: 10.1002/1097-0142(197803)41:3<941::aid-cncr2820410323>3.0.co;2-m

✦ Synopsis

The records of 1,497 patients with histologically proven adenocarcinoma of the stomach were reviewed from Charity Hospital over the 25-year period, 1948 to 1973. The operability rate was 82% and the resectability rate was 48%. In this series gastric carcinoma predominated in males and Negroes. Necropsy studies indicate a similar frequency of involvement of various organs in patients not operated upon as well as those subjected to a prior operation, which suggests the need for some therapeutic endeavors aimed at a wider base than the primary organ. The five-year survival rate, 7.4 overall, varied from 2.0% after esophagogastrectomy to 22.1% after radical subtotal gastrectomy, and to 30.3% for those with localized disease. One hundred one patients survived five years or more, and 5.4% survived ten years or more after the diagnosis of gastric cancer. Radical subtotal gastrectomy gave the best results in this series, whether measured in terms of median survival, five-year survival, or operative mortality. Esophagogastrectomy and by-pass procedures had high mortality and low survival rates, and should be reserved for special conditions.