๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Adeno-associated virus vectors

โœ Scribed by Barrie J. Carter


Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
779 KB
Volume
3
Category
Article
ISSN
0958-1669

No coin nor oath required. For personal study only.

โœฆ Synopsis


Adeno-associated virus is a human parvovirus that integrates its DNA genome into host cell chromosomes with very high efficiency. This suggests that adeno-associated virus may be a useful vector for human gene therapy. Interest in adeno-associated virus vectors increased greatly in the last year following reports that adeno-associated virus genome integration may be site specific and occur at preferred sites in the human genome. Several genes relevant to the treatment of genetic or infectious diseases have been expressed in adeno-associated virus vectors in vitro.


๐Ÿ“œ SIMILAR VOLUMES


Gene transfer into guinea pig cochlea us
โœ Masaya Konishi; Kohei Kawamoto; Masahiko Izumikawa; Hiromichi Kuriyama; Toshio Y ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 384 KB

## Abstract ## Background Several genes are candidates for treating inner ear diseases. For clinical applications, minimally invasive approaches to the inner ear are desirable along with minimal sideโ€effects. ## Methods Adenoโ€associated virus (AAV) was used as a vector into the guinea pig inner

Scalable production of adeno-associated
โœ Joon Young Park; Byung-Pil Lim; Kyuhyun Lee; Young-Gun Kim; Eui-Cheol Jo ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 390 KB

## Abstract Vectors derived from adenoโ€associated virus type 2 (AAV2) are promising gene delivery vehicles, but it is still challenging to get the large number of recombinant adenoโ€associated virus (rAAV) particles required for large animal and clinical studies. Current transfection technology requ

Gene transfer into rabbit arteries with
โœ Marcin Gruchaล‚a; Shalini Bhardwaj; Katri Pajusola; Himadri Roy; Tuomas T. Rissan ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 352 KB

## Abstract ## Background Gene transfer offers considerable potential for altering vessel wall physiology and intervention in vascular disease. Therefore, there is great interest in developing optimal strategies and vectors for efficient, targeted gene delivery into a vessel wall. ## Methods We