Adeno-associated virus as a gene delivery system
โ Scribed by Matthew J During
- Book ID
- 114176437
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 226 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0169-409X
No coin nor oath required. For personal study only.
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Several gene delivery vehicles are being developed for somatic gene therapy and each of these vectors has unique properties which makes them appropriate for different human disease applications. Recombinant adenoassociated viral (rAAV) vectors are proving themselves to be safe and efยฎcacious for the
In contrast to other gene delivery systems, adeno-associated virus vectors show long term gene expression without immune response or toxicity. New production methods have increased vector titers and eliminated adenovirus contamination, thereby facilitating effective in vivo use. These advancements w