As part of a study on additions to strained olefins and synthesis of strained nitrogen heterocycles, we have found that addition of methoxycsrbonylnitrene to 1,2dimethylcyclobutene, 2, and l-methylcyclobutene, 2, provides a convenient synthesis of the corresponding 5-azabicyclo[2.l.O]pentanes 2a and
Additions and Corrections- 1-Aryl-3-azabicyclo-[3.1.0]hexanes, a New Series of Nonnarcotic Analgesic Agents
โ Scribed by Epstein, Joseph; Brabander, Herbert; Fanshawe, William; Hofmann, Corris; McKenzie, Thomas; Safir, Sidney; Osterberg, Arnold; Cosulich, D; Lovell, F
- Book ID
- 111975510
- Publisher
- American Chemical Society
- Year
- 1982
- Tongue
- English
- Weight
- 155 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0022-2623
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๐ SIMILAR VOLUMES
## Abstract __Herein we report a detailed description of the structureโactivity relationships for a novel series of โCโlinkedโ 1,2,4โtriazolylazabicyclo[3.1.0]hexanes. These derivatives are endowed with very high inโ vitro affinity and selectivity for the dopamine D~3~ receptor. An optimization with
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