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Additional dystrophin fragment in Becker muscular dystrophy patients: Correlation with the pattern of DNA deletion

✍ Scribed by Vainzof, Mariz ;Passos-Bueno, Maria Rita ;Rapaport, Debora ;Pavanello, Rita C. M. ;Zatz, Mayana ;Bulman, Dennis E.


Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
296 KB
Volume
44
Category
Article
ISSN
0148-7299

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Pattern of deletions of the dystrophin g
✍ Coral-Vázquez, Ramón; Arenas, Diego; Cisneros, Bulmaro; Peñaloza, Laura; Salaman 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 416 KB 👁 3 views

We have analyzed 59 unrelated Mexican Duchenne/Becker muscular dystrophy patients (DMD/BMD) using PCR analysis of the 2 prone deletion regions in the DMD gene. Thirty one (52%) of the patients had a deletion of one or several of the exons. Most of the alterations (87%) were clustered in exons 44-52,