Addition of tetrachloromethane to oct-1-ene initiated by amino alcohols
β Scribed by I. G. Tarkhanova; M. G. Gantman; A. O. Chizhov; V. V. Smirnov
- Book ID
- 106520251
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 477 KB
- Volume
- 55
- Category
- Article
- ISSN
- 1573-9171
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## Abstract (__S__)β(1βBenzylpyrrolidinβ2βyl)diphenylmethanol and cinchonine were evaluated as promotors in the asymmetric additions of phenylacetylene to ketones, in order to prepare chiral propargylic alcohols. Good yields (up to 89%) and moderate enantioselectivities (up to 77.9% __ee__) were ac
vinyl-H) and 4.88 T (s) (tert-H) with relative intensities of 3: 1. When the solution is cooled to -54OC the signal from H-7 and H-8 is split reversibly into a doublet plus a singlet, the areas of which indicate a 54:46 equilibrium of endo-cisand exo-cis-dichlorides (boat form), the coalescence temp