Addition of diphenyl phosphinous acid to tetracyclone
โ Scribed by J.A. Miller
- Publisher
- Elsevier Science
- Year
- 1969
- Tongue
- French
- Weight
- 189 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
A very mild and facile method for the preparation of phosphinic acids via Michael addition of phosphonous acids as well as esters, through an intermediate silyl alkyl phosphonite, to activated conjugated systems is described.
Secondary phosphines 1-3 react readily with N-vinylpyrroles 4 and 5 under radical initiation to give regiospecifically anti-Markovnikov adducts, diorganyl-2-(1-pyrrolyl)ethylphosphines 6a-d, highly reactive building blocks for organic synthesis, in 88-91% yields.
Primary and secondary phosphines add regio-and stereospecifically to phenylcyanoacetylene and 4-hydroxy-4-methylpent-2ynenitrile under mild conditions to form corresponding functionalized secondary and tertiary phosphines of Z-configuration in 70 -91% yield. According to ESR and UV data, the additio