The poorly reactive 2,2,2 trifluorodiazoethane is able to add to unactivated aldehydes provided that the reaction is performed in presence of Lewis acids. This condensation leads mainly to homologated ketones and aldehydes a substituted by a trifluoromethyl group. 1) Lewis acid 0 CF3CHN2 + RCHO .
โฆ LIBER โฆ
Addition of cyclopropylphosphonates to aldehydes
โ Scribed by Hirao, Toshikazu; Nakamura, Toru; Hagihara, Masahiko; Agawa, Toshio
- Book ID
- 115463791
- Publisher
- American Chemical Society
- Year
- 1985
- Tongue
- English
- Weight
- 428 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0022-3263
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