Addition of bromine to β′-(functional alkyl) α,β-unsaturated esters stereoselective synthesis of β-haloderivatives
✍ Scribed by Taïcir Ben Ayed; Hassen Amri; Mohamed Moncef El Gaied
- Book ID
- 108372581
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- French
- Weight
- 383 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0040-4020
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📜 SIMILAR VOLUMES
Ethyl a-phenylchalcogeno a,b-unsaturated esters were prepared in a stereoselective manner by the reaction of ethyl propiolates with organocuprates, followed by the reaction with the appropriate electrophilic organosulfur, organoselenium or organotellurium source.
We recently reported the first examples of conjugate additions of alkyl sulphoxides to unsaturated esters,\* These reactions proceed with good selectivity and provide a promising new method for carrying out
Conjugate additions and conjugate ad$ition-alkylations proceed with very high stereoselectivity to a,&unsaturated acyls of n -CpFe(CO)(PPh ). 2 Oxidative cleavage of the products provides high yields of organic acid derivatives (es ers, B-lactams) with almost complete control of relative stereochem