Adaptive regulation of ascorbate transport in osteoblastic cells
โ Scribed by S. Jeffrey Dixon; John X. Wilson
- Book ID
- 112118934
- Publisher
- American Society for Bone and Mineral Research
- Year
- 2009
- Tongue
- English
- Weight
- 632 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0884-0431
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Ascorbic acid (AA) is an essential cofactor for osteoblast differentiation both in vivo and in vitro. Before it can function, this vitamin must be transported into cells via a specific Na / -dependent AA transporter. In this study, we examine the regulation of this transport activity by glucocortico
The clonal subtypes of cells in the osteogenic family represented by fibroblastoid , and mature osteoblastic MBA-15.6 cells were used to study the effects of glucocorticoid (dexamethasone). The role of dexamethasone was monitored on cell attachment when plated on various protein substrata (BSA, coll