ADAMTS13 activity and the risk of thrombotic thrombocytopenic purpura relapse in pregnancy
โ Scribed by Rachna Raman; Shangbin Yang; Haifeng M. Wu; Spero R. Cataland
- Book ID
- 108677140
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 60 KB
- Volume
- 153
- Category
- Article
- ISSN
- 0007-1048
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Congenital thrombotic thrombocytopenic purpura (TTP) (also known as Upshaw-Schulman syndrome, USS) is a rare, life-threatening disease characterized by thrombocytopenia and microangiopathic hemolytic anemia, associated with the deficiency of the von Willebrand factor-cleaving protease (ADAMTS13) due
Background and Objectives: Thrombotic thrombocytopenic purpura (TTP) is a clinical diagnosis that can be difficult to establish in severely ill patients. We report a case of fulminant TTP in a woman who died before receiving plasma exchange. An autopsy plasma sample was analyzed for ADAMTS13 activit