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Acylation of Some Thiophenes with Crotonyl Chloride

✍ Scribed by Bradsher, Charles K.; Brown, Frances C.; Grantham, R. J.


Book ID
121459783
Publisher
American Chemical Society
Year
1949
Tongue
English
Weight
273 KB
Volume
71
Category
Article
ISSN
0002-7863

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The regtochemist~' of aza-annulation of enaminones with ct,l~-unsaturated acid chlorides Ioearing hydrogen atoms on the y-carbon is reversed s~hen triethylamine is used as mediator. When the reaction was carried out at lower temperatures a 3-acyl J:Ly-unsaturated compound could be isolated which ~cl