Thirty-five patients with long-standing deep stromal herpes simplex keratitis were treated with 3% acyclovir ointment and corticosteroids. All patients were cured in 2 to 4 weeks, independent of both the duration of the keratitis before acyclovir therapy and the previous antiviral medication. Cortic
Acyclovir treatment in stromal herpetic keratitis
β Scribed by R. Ganswijk; J. A. Oosterhuis; M. Swart-Van Berg; J. Versteeg
- Publisher
- Springer-Verlag
- Year
- 1983
- Tongue
- English
- Weight
- 205 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0012-4486
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β¦ Synopsis
Twenty-five patients with long standing deep stromal herpetic keratitis and iritis were treated with acyclovir (3%) ointment and corticosteroids. All patients healed in about two to four weeks, independent of the duration of the keratitis before acyclovir treatment and independent of the antiviral medication given previously. Recurrences could not be prevented by acyclovir treatment. No serious side effects of acyclovix were noted.
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The measurement of the local IgG response in ocular Herpes simplex virus infection presents particular problems due to the difficulty in obtaining sufficient tear samples and the possible transudation of IgG from the serum to the inflamed eye. Using specific monoclonal antibodies to Human IgG subcla