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Acyclic analogs of nucleosides. Synthesis of 1,5-dihydroxy-3-oxa-2-pentyl derivatives of nucleic bases

✍ Scribed by S. G. Zavgorodnii; E. V. Efimtseva; S. N. Mikhailov; T. L. Tsilevich; A. É. Yavorskii; V. L. Florent'ev


Publisher
Springer US
Year
1988
Tongue
English
Weight
394 KB
Volume
24
Category
Article
ISSN
0009-3122

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Acyclic analogs of nucleosides. Synthesi
✍ S. N. Mikhailov; N. B. Grishko 📂 Article 📅 1988 🏛 Springer US 🌐 English ⚖ 348 KB

Pyrimido [5,4-c]quinol-4-one (II). A\_: To a solution of 0.5 g (2o58 mmole) of the pyrimidone (V) in 5 ml of glacial acetic acid was added 0.3 ml of a 10% solution of dimethylamine in dry benzene, and the mixture was boiled for 4 h, evaporated, triturated with water, and the (II) (0.37 g, 74%) filte