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Palladium—catalyzed synthesis of 3-methylene-1-oxa-2-phosphacycloalkane-2-oxide derivatives — the phosphorus analogs of α-methylenelactones

✍ Scribed by Yuanyao Xu; Zhong Li


Publisher
Elsevier Science
Year
1986
Tongue
French
Weight
229 KB
Volume
27
Category
Article
ISSN
0040-4039

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✍ Jean-Noël Collard; Claude Benezra 📂 Article 📅 1982 🏛 Elsevier Science 🌐 French ⚖ 266 KB

We thought we could use the same approach, by replacing the bromo-methacrylate derivative with a phosphonate such as 3, containing an allylic bromide. The synthesis of this compound was readily accomplished by the NBS bromination6 of ethylenlc phosphonate4 . The latter could be obtained by SOC12/py