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Acute urticaria and hepatitis complicating high-dose methotrexate therapy

✍ Scribed by Al-Lamki, Zakiya ;Thomas, Eileen ;El-Banna, Nagwa ;Jaffe, Norman

Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
362 KB
Volume
24
Category
Article
ISSN
0098-1532

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✦ Synopsis

Abstract

We report an unusual case of anaphylaxis and hepatitic dysfunction in a child with the administration of the twenty‐third course of high‐dose methotrexate. The latter had been used as an adjuvant to prevent pulmonary metastases and the prior 22 courses had been well tolerated. An attempt to reinstate methotrexate after the twenty‐third course was again followed by a similar reaction. Β© 1995 Wiley‐Liss, Inc.

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