## Abstract Seventyβthree pediatric patients with acute hepatitis and 19 control patients without liver disease living in Cairo, Egypt, were evaluated with a newly developed Western blot assay for IgM antibody to hepatitis E virus (IgM antiβHEV). The mean age of acute hepatitis patients was 6.4 yea
Acute sporadic hepatitis in Sudanese children
β Scribed by K. C. Hyams; M. A. M. Hussain; M. A. Al-Arabi; N. Al-Huda Atallah; A. El-Tigani; M. C. McCarthy
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 398 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0146-6615
No coin nor oath required. For personal study only.
β¦ Synopsis
Eighty consecutive cases of acute viral hepatitis and 80 controls selected from a public pediatric clinic were entered into a study of acute sporadic hepatitis in Khartoum, Sudan. Study subjects were 14 years of age or younger and were mainly from a low socioeconomic level. Non-A, non-B hepatitis was diagnosed by exclusion in 35 (43.8%) patients, hepatitis A in 27 (33.8%), acute hepatitis B in 8 (10.0%), possible Epstein-Barr virus (EBV) hepatitis in 1 patient; and dual hepatitis A and B infection in 1 patient. Eight acute cases were positive for HBsAg but negative for anti-HBc IgM and anti-HAV IgM. Delta hepatitis was not identified in any study subject. A household case of jaundice and acquaintance with an individual outside of the household with jaundice during the prior 6 months were associated with non-A, non-B hepatitis. There was no association between parenteral exposure and non-A, non-B hepatitis. These findings suggest that enterically transmitted non-A, non-B hepatitis may be a major cause of acute sporadic hepatitis in children in this area, as well as a cause of epidemic hepatitis.
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