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Acute promyelocytic leukemia with t(15;16;17;19) and unusual fluorescence in situ hybridization pattern with PML and RARA probes

✍ Scribed by Nazmi Ragheb Kamal; Curtis A. Hanson; Gordon W. Dewald


Book ID
114136040
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
431 KB
Volume
92
Category
Article
ISSN
0165-4608

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RARA and PML gene rearrangements in acut
✍ Dr. Christopher D. McKinney; Michael E. Williams; Wendy L. Golden; Nicholas W. G πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 597 KB

The translocation t( IS; 17) associated with acute promyelocytic leukemia (APL) results in fusion of the retinoic acid receptor alpha (RARA) gene on chromosome I7 with the putative transcription factor gene. PML, on chromosome IS. We report three cases of APL with complex cytogenetic translocations