## BACKGROUND. Extramedullary acute promyelocytic leukemia (APL) is rare, and said to be more common after treatment with all-trans retinoic acid (ATRA) than after any other treatment. ## METHODS. The case of a child with extramedullary relapse of APL after initial treatment with ATRA and that
Acute promyelocytic leukemia
β Scribed by Dan Douer
- Book ID
- 107531638
- Publisher
- Springer
- Year
- 2000
- Tongue
- English
- Weight
- 266 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1527-2729
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π SIMILAR VOLUMES
Because extramedullary depositions of APL are uncommon, information concerning the therapeutic Department of Orthopaedics University Ho Λpital H. Mondor role of ATRA in extramedullary disease is insufficient. In their article, Wiernik et al. state that at least one Creteil, France Gaetano Bacci, M.D
## Abstract Sixteen children (ages 2β17) with acute promyelocytic leukemia (APL) were studied retrospectively. Diagnosis was based on clinical features and morphological criteria of the FAB classification. Bleeding diathesis was the predominant presenting symptom (>85%), associated with laboratory