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Acute nephrotoxicity of aristolochic acids in mice

✍ Scribed by Noriko Sato; Daisuke Takahashi; Reiko Tsuchiya; Takuya Mukoyama; Shin-ichi Yamagata; Nobunori Satoh; Shiro Ueda; Shih-Ming Chen; Makoto Ogawa; Masaaki Yoshida; Seizo Kondo

Book ID
111769088
Publisher
Pharmaceutical Press
Year
2004
Tongue
English
Weight
715 KB
Volume
56
Category
Article
ISSN
2042-7158

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## Abstract Ingestion of aristolochic acids (AA) contained in herbal remedies results in aristolochic acid nephropathy (AAN), which is characterized by chronic renal failure, tubulointerstitial fibrosis and urothelial cancer. AA I and AA II, primary components in AA, have similar genotoxic potentia

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