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Acute myeloid leukemia (AML-M2) with t(5;11)(q35;q13) and normal expression of cyclin D1

✍ Scribed by Fábio Morato de Oliveira; Luiz Gonzaga Tone; Belinda Pinto Simões; Roberto Passetto Falcão; María Sol Brassesco; Elza Tiemi Sakamoto-Hojo; Guilherme Augusto Silva dos Santos; André Fiorin Marinato; Rafael Henriques Jácomo; Eduardo Magalhães Rego

Book ID
113513039
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
374 KB
Volume
172
Category
Article
ISSN
0165-4608

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The CDCREL1 gene fused to MLL in de novo acute myeloid leukemia with t(11;22)(q23;q11.2) and its frequent expression in myeloid leukemia cell lines
✍ Ken Tatsumi; Tomohiko Taki; Masafumi Taniwaki; Hideo Nakamura; Jun Taguchi; Ying 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 124 KB 👁 1 views

We report on an adult patient with de novo acute myeloid leukemia (AML) with a t(11;22)(q23;q11.2) involving CDCREL1 and MLL genes. Reverse transcriptase (RT)-polymerase chain reaction (PCR) followed by direct sequencing analysis revealed the MLL-CDCREL1 fusion transcript in his leukemic cells. Anal