Acute megakaryoblastic leukemia in children and adolescents, excluding Down's syndrome: improved outcome with intensified induction treatment
β Scribed by Reinhardt, D; Diekamp, S; Langebrake, C; Ritter, J; Stary, J; Dworzak, M; Schrauder, A; Zimmermann, M; Fleischhack, G; Ludwig, W-D
- Book ID
- 110056337
- Publisher
- Nature Publishing Group
- Year
- 2005
- Tongue
- English
- Weight
- 73 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0887-6924
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π SIMILAR VOLUMES
Of 2947 children with acute lymphocytic leukemia (ALL), treated during three consecutive studies of the Pediatric Oncology Group (1974-1986), 52 (1.8%) had Down's Syndrome (DS). Comparison of clinical and laboratory characteristics showed no significant differences in leukocyte count, racial distrib
## Abstract ## BACKGROUND. Children with Down syndrome (DS) have from 10 to 20 times the risk of developing acute leukemia than the general pediatric population. There is mixed evidence for associations between reproductive history or infertility and acute leukemia among children without DS. ## M