Acute lymphoblastic leukemia. The significance of nuclear convolutions
β Scribed by Gerassimos A. Pangalis; Bharat N. Nathwani; Henry Rappaport; Robert B. Rosen
- Publisher
- John Wiley and Sons
- Year
- 1979
- Tongue
- English
- Weight
- 618 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0008-543X
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Frequencies of all defined HLA-A, -B, -C (-DR) antigens were determined in 142 (59) Germans suffering from acute lymphoblastic leukemia (ALL) with differentiation of immunologically defined or age-related subgroups of the disease. A highly significant rise of the HLA-C locus antigen Cw7 was found in
Chromosome studies, using bone marrow samples of 26 pretreated children (below 15 years of age) with Acute Lymphoblastic Leukemia were carried out to explore the potentialities of applying chromosomal findings as a prognostic indicator in these patients. Abnormal karyotype was identified in 15 patie