The human trithorax homolog gene (MLL) is directly involved in over 90% of cases of acute leukemia with abnormalities of I I q23. However, involvement of other genes at I I q23 both centromeric and telomeric of MLL has been identified in different subtypes of leukemia and lymphoma. We describe a cas
β¦ LIBER β¦
Acute leukemia with t(10;11)(p11-p15;q13-q23)
β Scribed by Christiane Secco; Peter H. Wiernik; John M. Bennett; Elisabeth Paietta
- Book ID
- 113253621
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 498 KB
- Volume
- 86
- Category
- Article
- ISSN
- 0165-4608
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## Abstract Thirteen cosmid probes were mapped on the long arm of chromosome 11 between 11q22 and 11q24 by nonradioactive in situ hybridization. Starting with these localizations and those of other probes mapped to 11q23, four acute leukemias with translocations involving 11q23 were studied with th