๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Acute effect of 8-methoxypsoralen and ultraviolet light on sister chromatid exchange

โœ Scribed by H. C. Wulf

Publisher
Springer-Verlag
Year
1978
Tongue
English
Weight
922 KB
Volume
263
Category
Article
ISSN
0340-3696

No coin nor oath required. For personal study only.

โœฆ Synopsis

The acute effect of 8-methoxypsoralen (8-MOP) and 8-MOP + long wave ultraviolet light (UVA) on sister chromatid exchange (SCE) has been examined in an in vitro experiment. The SCE count was significantly increased by 8-MOP without light, but the effect was substantially greater (50%) by 8-MOP + UVA. In addition, mitoses with banded staining of the chromosomes were seen after 8-MOP and UVA. These changes were dose dependent, and they might be responsible for the reduced cell turnover in psoriasis plaque after PUVA.

๐Ÿ“œ SIMILAR VOLUMES

Effects of acute and chronic administrat
Effects of acute and chronic administration of mitomycin C on the induction of sister chromatid exchanges in vivo
โœ Kram, David ;Bynum, Gaither D. ;Dean, Roger ;Schneider, Edward L. ;Farland, Will ๐Ÿ“‚ Article ๐Ÿ“… 1981 ๐Ÿ› Wiley (John Wiley & Sons) โš– 407 KB ๐Ÿ‘ 2 views

## Abstract Frequencies of sister chromatid exchanges (SCE) were analyzed in bone marrow cells of mice injected with mitomycin C (MMC) both before and during infusion with bromodeoxyuridine (BrdU). Administration of MMC at 1, 6.5, and 13 hours after the onset of BrdU infusion resulted in the induct

Effect of diesel exhaust emissions, part
Effect of diesel exhaust emissions, particulates, and extract on sister chromatid exchange in transplacentally exposed fetal hamster liver
โœ Pereira, Michael A. ;McMillan, Lofton ;Kaur, P. ;Gulati, D. K. ;Sabharwal, P. S. ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› Wiley (John Wiley & Sons) โš– 358 KB

## Abstract The genotoxic activity of diesel exhaust emissions, particulate matter, and an organic extract of the particulate matter was evaluated in transplacentally exposed Syrian hamster fetal liver cells. The frequency of sister chromatid exchange (SCE) was determined on day 13 of gestation. Th

Effects of auxin and cytokinin on induct
Effects of auxin and cytokinin on induction of sister chromatid exchanges in cultured cells of wheat (Triticum aestivumL.)
โœ M. Murata ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› Springer ๐ŸŒ English โš– 680 KB

In order to know the mutagenic effects of synthetic auxins (NAA, 2,4-D, and 2,4,5-T) and a cytokinin (kinetin) in vitro, sister chromatid exchanges (SCEs) were analyzed in cultured cells of a hexaploid wheat (Triticum aestivum L.). In the MS medium supplemented with 2.0 mg/l 2,4-D, the mean number o