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Acute colchicine and vinblastine toxicity in 6-sulfanilamidoindazole-pretreated rats

✍ Scribed by Morgan L. Miller; Raymond N. Hiramoto; Seng-Jaw Soong; Cecil O. Samuelson Jr.; John R. Ward

Book ID
113205684
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
787 KB
Volume
60
Category
Article
ISSN
0041-008X

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## Abstract The oral toxicity of a single administration by gavage (10, 20 or 30 mg kg^βˆ’1^ body weight) of colchicine (COL) was determined in young, mature male and female Sprague‐Dawley rats. The effect of COL was evaluated in the presence or absence of additional treatment variables that included