Acute and subacute inhalation toxicity of silane 1000 ppm in mice
β Scribed by Kazuyuki Omae; Tohru Sakai; Haruhiko Sakurai; Kazuto Yamazaki; Toshikatsu Shibata; Koji Mori; Mitsuhiro Kudo; Hirokazu Kanoh; Masatomo Tati
- Publisher
- Springer-Verlag
- Year
- 1992
- Tongue
- English
- Weight
- 357 KB
- Volume
- 66
- Category
- Article
- ISSN
- 0340-5761
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The effects of acute and subchronic administration of thymoquinone (TQ), the main constituent of the volatile oil of the black seeds Nigella sativa, with significant cytoprotective properties, were studied in male Swiss albino mice. After acute oral administration, the LD 50 value (95% CL) was 2.4
Sprague-Dawley rats were given 15, 70 and 140 min exposures to 15 mg/l 3,3-dimethyl-2-butanol, pinacolyl alcohol (PA), or 6-hour exposures to 0.2, 1.0 and 5.0 mg/l PA (1 mg/l = 240 ppm). A 50% mortality rate was obtained at the longest exposure to 15 mg/l. Sex related differences in the blood levels