✦ LIBER ✦

Acute and chronic hepatitis delta virus infection: Direct or indirect effect on hepatitis B virus replication?

✍ Scribed by Patrizia Farci; Peter Karayiannis; M. Eliana Lai; Francesco Marongiu; Giuseppina Orgiana; Angelo Balestrieri; Howard C. Thomas

Publisher: John Wiley and Sons
Year: 1988
Tongue: English
Weight: 605 KB
Volume: 26
Category: Article
ISSN: 0146-6615
DOI: 10.1002/jmv.1890260308

No coin nor oath required. For personal study only.

✦ Synopsis

In a large population of patients, chronic hepatitis delta virus (HDV) infection was usually associated with absence of hepatitis B virus (HBV) replication. However, acute HDV superinfection progressing to chronic HDV infection in two hepatitis B e antigen (HBeAg)-positive HBV carriers and coinfection in two other patients who progressed to chronic HBV (HBeAg-positive) and HDV infection was associated with continuing high-level HBV replication for several years. Thus HDV infection does not always inhibit HBV replication. The hypothesis that the different effects of HDV coinfection and superinfection on HBV replication may stem from variability in the capacity of the host to produce and respond to interferon is discussed.

📜 SIMILAR VOLUMES

Hepatitis b virus replication in acute h

Hepatitis b virus replication in acute hepatitis B, acute hepatitis B virus-hepatitis delta virus coinfection and acute hepatitis delta superinfection

✍ J. Genesca; R. Jardi; M. Buti; L. Vives; S. Prat; J. I. Esteban; R. Esteban; J. 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 English ⚖ 501 KB

To evaluate the effect of hepatitis delta virus on the level of replication of hepatitis B virus and to assees the clinical significance that such an effect might have on the find oatcome of the infection, the serological profile of hepatitis B virus DNA was investigated in 153 patients with acute o

Hepatitis B virus DNA, HBeAg and delta i

Hepatitis B virus DNA, HBeAg and delta infection during the course from acute to chronic hepatitis B virus infection

✍ Kim Krogsgaard; Jan Aldershvile; Peter Kryger; Poul Andersson; Jens Ole Nielsen; 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 English ⚖ 547 KB

The presence of hepatitis B virus DNA in serum was determined in 57 unselected patients during the course from acute to chronic hepatitis B infection. Forty-six (81%) patients were hepatitis B virus DNA-positive in the first available serum sample. Generally, hepatitis B virus DNA was cleared before

Leucocyte hepatitis B virus DNA in acute

Leucocyte hepatitis B virus DNA in acute and chronic hepatitis B virus infection

✍ F. Davison; G. J. M. Alexander; Ch. Anastassakos; E. A. Fagan; Roger Williams 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 English ⚖ 444 KB 👁 1 views

In the present study we have investigated 53 patients with a spectrum of acute and chronic hepatitis B virus (HBV) infection for the presence of leucocyte HBV-DNA with the aid of molecular techniques. HBV-DNA was detected in peripheral blood mononuclear cells of 31 of 45 (69%) of chronic HBsAg carri

Concurrent hepatitis C virus and hepatit

Concurrent hepatitis C virus and hepatitis delta virus superinfection in patients with chronic hepatitis B virus infection

✍ Yun-Fan Liaw; Rong-Nan Chien; Tong-Jong Chen; I-Shyan Sheen; Chia-Ming Chu 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 476 KB 👁 1 views

## Abstract Since hepatitis C virus (HCV) and hepatitis delta virus (HDV) are transmitted by the same routes as hepatitis B virus (HBV), simultaneous or concurrent HCV and HDV infection in patients with chronic HBV infection may occur. To test this hypothesis and to examine the clinicohistological

IgA class antibodies to hepatitis delta

IgA class antibodies to hepatitis delta virus antigen in acute and chronic hepatitis delta virus infections

✍ Dr. Ian G. McFarlane; Kanchan Chaggar; Susan E. Davies; Heather M. Smith; Graeme 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 510 KB

Sera from 31 patients with chronic hepatitis delta virus infection and 18 patients with acute hepatitis delta virus infection were examined for IgA class antibodies to this virus using a newly developed enzyme immunoassay. IgA antibody to hepatitis D virus was detected in 21 (67.7%) of 31 patients w

Liver disease activity and hepatitis B v

Liver disease activity and hepatitis B virus replication in chronic delta antigen-positive hepatitis B virus carriers

✍ Stephanos J. Hadziyannis; Morris Sherman; Harvey M. Lieberman; David A. Shafritz 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 English ⚖ 480 KB 👁 2 views

Delta antigen is currently thought to reflect superinfection of the liver with a defective RNA virus (delta agent), requiring helper function from hepatitis B virus for its replication. To assess the influence of delta agent on hepatitis B virus replication in patients persistently infected with bot