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Activity of the Raf Kinase Inhibitor BAY 43-9006 in Patients with Advanced Solid Tumors

โœ Scribed by Heather DeGrendele; Edward Chu; John Marshall


Book ID
119616956
Publisher
CIG Media Group, LP.
Year
2003
Tongue
English
Weight
131 KB
Volume
3
Category
Article
ISSN
1533-0028

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โœ Strumberg, D. ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› American Society of Clinical Oncology ๐ŸŒ English โš– 207 KB

## Purpose BAY 43-9006 is a novel dual-action Raf kinase and vascular endothelial growth factor receptor inhibitor that inhibits tumor cell proliferation and angiogenesis. This study established the safety and pharmacokinetics of BAY 43-9006 in 69 patients with advanced refractory solid tumors.