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Activity of sulfa drugs and dihydrofolate reductase inhibitors againstCandida albicans

โœ Scribed by Karen Bush; Joan S. Freudenberger; Dorothy S. Slusarchyk; R. B. Sykes; E. Meyers


Publisher
Springer
Year
1982
Tongue
English
Weight
234 KB
Volume
38
Category
Article
ISSN
1420-682X

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## Abstract Three previously undescribed dihydrofolate reductase (DHFR) inhibitors, N^ฮฑ^โ€[4โ€[__N__โ€[(2,4โ€diaminopyrrolo[2,3โ€__d__]pyrimidinโ€5โ€yl)methyl]amino]benzoyl]โ€__N__^ฮด^โ€hemiphthaloylโ€Lโ€ornithine **(7)**, __N__^ฮฑ^โ€ [4โ€ [__N__โ€[(2,4โ€diaminothieno[2,3โ€__d__]pyrimidinโ€5โ€yl)methyl]amino]benzoyl]โ€