Determination of the Hydrophobicity of L
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Qing C. Meng; Helen Zou; Jonas S. Johansson; Roderic G. Eckenhoff
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Article
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2001
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Elsevier Science
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English
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Hydrophobicity, a term used to describe a fundamental physicochemical property of local anesthetics, was in the past obtained by octanol/buffer partitioning. It has been suggested that the octanol method, despite its obvious advantages, also has some drawbacks. HPLC has become an attractive alternat