Activity of indicine N-oxide in refractory acute leukemia
โ Scribed by Louis Letendre; William A. Smithson; Gerald S. Gilchrist; E. Omer Burgert Jr.; Clark H. Hoagland; Matthew M. Ames; Garth Powis; John S. Kovach
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- English
- Weight
- 432 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Two groups of children with refractory acute lymphoblastic leukemia were treated with a regimen of methotrexate (MTX) and asparaginase (Asn'ase) based on studies of the effect of MTX in vitro on human lymphoblasts exposed to Asn'ase. Induction therapy in 12 children produced 4 complete remissions, 3
Neutrophil (PMN) bactericidal activity, phagocytosis, and nitroblue tetrazolium (NBT) reduction were evaluated in 18 children with untreated or relapsing acute leukemia and 20 children in hematologic remission. Half of the patients in relapse demonstrated abnormal PMN bactericidal activity, while re
## Abstract The clinical outlook for adults with acute lymphoblastic leukemia (ALL) has Improved with the use of intensive chemotherapy. Complete remissions (CR) are achieved in 80% of adults but the majority relapse on maintenance chemotherapy and a few exhibit primary resistance to induction ther