The ability of Pneumocystis carinii to induce tumor necrosis factor (TNF)-a release by monocytes/macrophages from immunocompetent humans was investigated. Monocytes and monocyte-derived macrophages from healthy individuals produced an increased amount of TNF-a when exposed to P. carinii cysts obtain
Activity of human peritoneal macrophages against a human tumor: role of tumor necrosis factor-α, PGE2 and nitrite, in vitro studies
✍ Scribed by S. Ben-Efraim; C. Tak; M.J.W.A. Fieren; J.C. Romijn; I. Beckmann; I.L. Bonta
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 461 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0165-2478
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
In a previous study we showed that recombinant human tumor necrosis factor-a (rTNF-tr) has no cytolytic effect on Meth A fibrosarcoma cells in virro but that it has a strong anti-tumor activity in vivo. In the present work, we define the in vivo mode of action of rTNF-a on solid-form Meth A fibrosar
## Abstract ## Objectives/Hypothesis: Tumor necrosis factor–α (TNF‐α) is an inflammatory cytokine and apoptotic molecule that appears to be a mediator in inflammation and fibrosis. The objective of this investigation was to examine the effects of TNF‐α on 3D Carbylan‐GSX in vitro cultured human vo
Toxoplasrna gondii, an obligate intracellular parasite, is able to replicate in human brain cells. We recently showed that interferon (1FN)-y-activated cells from glioblastoma line 86HG39 were able to restrict Toxoplusma growth. The effector mechanism responsible for this toxoplasmostatic effect was