✦ LIBER ✦

Activity of Carbetimer in a human tumor cloning system

✍ Scribed by Daniel L. Kisner; Persis Mehta; G. Edward Paget; Daniel D. Hoff

Publisher: Springer US
Year: 1984
Tongue: English
Weight: 270 KB
Volume: 2
Category: Article
ISSN: 0167-6997
DOI: 10.1007/bf00173787

No coin nor oath required. For personal study only.

✦ Synopsis

The antitumor activity of Carbetimer was tested against 171 patient's tumors in a human tumor cloning system. Sixty-seven tumor specimens had adequate growth to be considered evaluable. In 21 specimens survival of tumor colony forming units was less than or equal to 50% that in control plates. Antitumor effect was most impressive in carcinomas of the breast, ovary, and lung. This information will be useful in planning disease oriented Phase II trials.

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