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Activity in clastogenicity and SCE assays, and aberration kinetics in chinese hamster V79-E cells

✍ Scribed by Rudolf Thust; Jürgen Mendel; Heide Schwarz; Rolf Warzok

Book ID
119092120
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
913 KB
Volume
79
Category
Article
ISSN
0165-1218

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Exogenous glutathione induces sister chr
Exogenous glutathione induces sister chromatid exchanges, clastogenicity and endoreduplication in V79-E Chinese hamster cells
✍ Rudolf Trust; Barbara Bach 📂 Article 📅 1985 🏛 Springer 🌐 English ⚖ 510 KB

Glutathione (GSH) dissolved in Eagle's MEM and added to cultures of V79-E cells in concentrations between 2.5 X 10 -4 and 10 -3 moles/l for 1 h induces a dose-dependent cell cycle delay, sister chromatid exchanges and clastogenic damage. 7-8% of the metaphases showed endoreduplication at a recovery