Activity-Dependent Transfer of Brain-Derived Neurotrophic Factor to Postsynaptic Neurons
โ Scribed by Kohara, K.
- Book ID
- 115530745
- Publisher
- American Association for the Advancement of Science
- Year
- 2001
- Tongue
- English
- Weight
- 464 KB
- Volume
- 291
- Category
- Article
- ISSN
- 0036-8075
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## Abstract To visualize the release dynamics of the brainโderived neurotrophic factor (BDNF) involved in neural plasticity, we constructed a plasmid encoding green fluorescent protein (GFP) fused with BDNF. First, several biological studies confirmed that this fusion protein (BDNFโGFP) mimics the
## Abstract Brainโderived neurotrophic factor (BDNF) belongs to the neurotrophin family and regulates the survival, differentiation, and maintenance of function in different neuronal populations. BDNF is strongly expressed in hypothalamic neurons, where it exerts longโ or shortโlasting actions. Bec