We have successfully designed and synthesized two fluorescently-labeled, activity-based probes, Probe 1 and Probe 2, which were shown to label protein tyrosine phosphatases specifically, as well as other types of phosphatases. The probes were not reactive towards the other non-phosphatase enzymes te
β¦ LIBER β¦
Activity-based probes that target diverse cysteine protease families
β Scribed by Kato, Daisuke; Boatright, Kelly M; Berger, Alicia B; Nazif, Tamim; Blum, Galia; Ryan, Ciara; Chehade, Kareem A H; Salvesen, Guy S; Bogyo, Matthew
- Book ID
- 109914014
- Publisher
- Nature Publishing Group
- Year
- 2005
- Tongue
- English
- Weight
- 344 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1552-4450
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