𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Activities of silymarin and its flavonolignans upon low density lipoprotein oxidizability in vitro

✍ Scribed by N. Škottová; V. Krečman; V. Šimánek

Book ID
101290954
Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
47 KB
Volume
13
Category
Article
ISSN
0951-418X

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✦ Synopsis

Silymarin, a standardized extract from Silybum marianum, inhibited in vitro the copper-induced oxidation of human LDL in a concentration-dependent manner. Silybin, a main flavonolignan of silymarin, appeared to be responsible for this LDL antioxidant effect. Silychristin and silydianin, other flavonolignans of silymarin, acted rather as pro-oxidants, but with regard to their content in silymarin, it did not contribute significantly to the reduction of the total LDL antioxidant capacity of silymarin.

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